{"id":722,"date":"2013-12-16T11:35:12","date_gmt":"2013-12-16T02:35:12","guid":{"rendered":"http:\/\/nagasakilab.csml.org\/en\/?page_id=722"},"modified":"2023-08-02T15:14:36","modified_gmt":"2023-08-02T06:14:36","slug":"introduction","status":"publish","type":"page","link":"https:\/\/nagasakilab.csml.org\/en\/introduction","title":{"rendered":"Introduction"},"content":{"rendered":"<div id=\"yass_top_edge_dummy\" style=\"width: 1px; height: 1px; padding: 0px; margin: -11px 0px 0px; border-width: 0px; display: block;\"><\/div>\n<div id=\"yass_top_edge\" style=\"background-image: url('chrome:\/\/yass\/content\/edgebgtop.png'); background-attachment: scroll; background-position: center bottom; padding: 0px; margin: 0px 0px 0px -247.5px; border-width: 0px; height: 0px; display: block; width: 1px;\"><\/div>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-2536\" src=\"https:\/\/nagasakilab.csml.org\/en\/wp-content\/uploads\/2023\/08\/Division_of_Biomedical_Analysis_en.png\" alt=\"Division of Biomedical Information Analysis\" width=\"1000\" height=\"563\" \/><\/p>\n<p>In 2000, the draft sequence of the human genome was published, and in 2022, the complete human genome reference sequence from telomere to telomere was finally published. Instruments for measuring human genome sequence information have made remarkable progress, and just one instrument can measure whole-genome information from more than thousands of individuals per year. It allows large-scale cohort studies to obtain the whole-genome data of millions of participants in Japan and overseas combined.<\/p>\n<p>In parallel, recent advances in measuring instruments at the single-cell level have led to remarkable progress in developing high-precision, large-scale information.<\/p>\n<p>Our laboratory mainly focuses on the following three research topics;<\/p>\n<ul>\n<li>large-scale life science data analysis by processing or developing the machine learning, deep learning, or quantum computing methods on the hybrid high-performance computing system.<\/li>\n<li>the application of biomedical informatics analysis related to clinical, e.g., cancer and rare diseases, and population scale cohort samples, e.g., common diseases.<\/li>\n<li>data analysis with systems biology to human data.<\/li>\n<\/ul>\n<p style=\"margin-top: 10px;\">On-the-job training in real-world datasets from (i) to (iii), students educate as next-generation human resources with data analysis skills to the large-scale human genome, omics, and clinical data from the latest technologies from the biomedical domain.<\/p>\n<p><strong>Biological and Medical Keywords\u00a0<\/strong><\/p>\n<p>Population Genetics \/ Statistical Genetics \/ Human Genetic Variation \/ eQTL Analysis \/ Spatial Transcriptomics \/ Spatial Proteomics \/Huge Scale Data Processing \/ High Performance Computing \/ Data-driven Knowledge Discovery \/ Multi-Omics Approach \/ Preventive Medicine<\/p>\n<p><strong>Information Science\u00a0<\/strong><\/p>\n<p>Otimization \/ Parameter Estimation<br \/>\nDiscovery Science \/ Data Mining<br \/>\nModeling \/ Petri net<br \/>\nFormat \/ XML \/ Ontology \/ OWL<br \/>\nData Structure and algorithm<br \/>\nModel Validation\/ Model Checking\/ Data Assimilation \/ Model Selection<br \/>\nDatabase<br \/>\nVisualization \/ Graph layout Algorithm \/ Hybrid Cloud Computing<br \/>\nHigh performance computing \/ Cloud computing<br \/>\nSoftware Development \/ Quantum Computing<\/p>\n<p><strong>Bioinformatics, Systems Biology related keywords<\/strong><\/p>\n<p>Metabolic Pathway \/ Signal Transduction Pathway \/ Gene Regulatory Network<br \/>\nBiological Pathway Modeling and Simulation<br \/>\nGene Expression Analysis<br \/>\nPathway Database<br \/>\nPathway Layout Algorithm<br \/>\nPathway Data Assimilation<br \/>\nPathway Model Validation and Checking<br \/>\nHiT-seq pipeline development<br \/>\nHiT-seq (DNA\/RNA\/Chip Sequence) Analysis<\/p>\n<p>eQTL Analysis<\/p>\n<p><strong>IT keywords<\/strong><\/p>\n<p>Java \/ Python \/ javascript \/ work flow engine \/ hybrid cloud comping \/ quantum computing<br \/>\nphp \/ tomcat \/ singularity \/ appainer \/ eclipse \/ scala \/ quantum secure cloud<br \/>\nmysql \/ postgresql \/ slurm \/ lustre \/ deep learning \/ large language model (LLM)<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In 2000, the draft sequence of the human genome was published, and in 2022, the complete human genome reference sequence from telomere to telomere was finally published. Instruments for measuring human genome sequence information have made remarkable progress, and just &hellip; <a href=\"https:\/\/nagasakilab.csml.org\/en\/introduction\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"passster_activate_protection":false,"passster_protect_child_pages":"","passster_protection_type":"password","passster_password":"","passster_activate_overwrite_defaults":"","passster_headline":"","passster_instruction":"","passster_placeholder":"","passster_button":"","passster_id":"","passster_activate_misc_settings":"","passster_redirect_url":"","passster_hide":"no","passster_area_shortcode":"","footnotes":""},"class_list":["post-722","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/nagasakilab.csml.org\/en\/wp-json\/wp\/v2\/pages\/722","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nagasakilab.csml.org\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/nagasakilab.csml.org\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/nagasakilab.csml.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nagasakilab.csml.org\/en\/wp-json\/wp\/v2\/comments?post=722"}],"version-history":[{"count":9,"href":"https:\/\/nagasakilab.csml.org\/en\/wp-json\/wp\/v2\/pages\/722\/revisions"}],"predecessor-version":[{"id":2538,"href":"https:\/\/nagasakilab.csml.org\/en\/wp-json\/wp\/v2\/pages\/722\/revisions\/2538"}],"wp:attachment":[{"href":"https:\/\/nagasakilab.csml.org\/en\/wp-json\/wp\/v2\/media?parent=722"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}