The 61st In Silico Megabank Research Seminar will be held on Thursday, April 16 . This Time, we will be welcoming Dr. Ichizo Kobayashi, Graduate School of Frontier Sciences, The University of Tokyo as our lecturer, and he will be speaking on \u201cEpigenetics-driven Evolution: Demonstration through OMICS Comparison of Multiple Sequences within Bacterial Species.\u201d<\/p>\n
\u30fbDate: Thursday, April 16, 2015 \uff0aThis lecture is transferable as a class in the medical research-related lecture course.<\/p>\n \u30fbAbstract : Concerning the adaptive evolution, a theory on the unit of evolution based on \u201cepigenetic state\u201d was developed in contrast to the idea of \u201cselection from various genomic sequencing.\u201d The epigenetic state was demonstrated in the study with bacteria that can directly pass on to the next generation.\u00a0 Many of DNA methylase of bacteria create restriction-modification system and restriction enzyme recognizes the same sequence. They are \u201cselfish\u201d epigenetics that destroy non-self epigenomes. Excluding cells from which restriction-modification system is excluded through chromosomal breaks forces host bacteria into the certain methylome. In our study, it was demonstrated that the restriction-modification system modulates the recognition sequence, alter the creation of methylome in various ways, and leads changes in the patterns of gene expressions and various phenotypes.\u00a0 Restriction of these restriction-modification systems from internal and external environment, a type of restriction enzyme that cuts bases out as is the case in demethylating enzyme of eukaryote, and degradation and alteration of rRNA genes used for metagenome analysis are also introduced; we would like to discuss the perception of microevolution of microbiome<\/p>\n \u30fbOrganizer : Yoko Kuroki, Masao Nagasaki<\/p>\n","protected":false},"excerpt":{"rendered":" The 61st In Silico Megabank Research Seminar will be held on Thursday, April 16 . This Time, we will be welcoming Dr. Ichizo Kobayashi, Graduate School of Frontier Sciences, The University of Tokyo as our lecturer, and he will be … Continue reading
\n\u30fbTime: 10:00 am\u201011:00 am
\n\u30fbVenue : Small Conference Room 2(3rd Floor), Tohoku Medical Megabank Building<\/a>
\n\u30fbTitle: Epigenetics-driven Evolution: Demonstration through OMICS Comparison of Multiple Sequences within Bacterial Species
\n\u30fbLecturer : Ichizo Kobayashi (Graduate School of Frontier Sciences, The University of Tokyo)<\/p>\n