{"id":2947,"date":"2015-06-26T14:13:34","date_gmt":"2015-06-26T05:13:34","guid":{"rendered":"http:\/\/nagasakilab.csml.org\/ja\/?p=2947"},"modified":"2023-12-08T09:50:23","modified_gmt":"2023-12-08T00:50:23","slug":"%e6%9c%ac%e4%ba%ba%e3%81%ab%e6%9c%80%e9%81%a9%e5%8c%96%e3%81%95%e3%82%8c%e3%81%9f%ef%bd%93%ef%bd%8e%ef%bd%90%e3%82%a2%e3%83%ac%e3%82%a4%e3%80%8c%e3%82%b8%e3%83%a3%e3%83%9d%e3%83%8b%e3%82%ab%e3%82%a2","status":"publish","type":"post","link":"https:\/\/nagasakilab.csml.org\/ja\/archives\/2947","title":{"rendered":"\u672c\u4eba\u306b\u6700\u9069\u5316\u3055\u308c\u305f\uff33\uff2e\uff30\u30a2\u30ec\u30a4\u300c\u30b8\u30e3\u30dd\u30cb\u30ab\u30a2\u30ec\u30a4\u00ae\u300d\u3092\u8a2d\u8a08\u301c\u7d0466\u4e07\u500b\u306eSNP\u60c5\u5831\u3092\u642d\u8f09\u3057\u305f\u500b\u5225\u5316\u4e88\u9632\u30fb\u533b\u7642\u7814\u7a76\u3092\u52a0\u901f\u3059\u308b\u89e3\u6790\u30c4\u30fc\u30eb\u301c\u3010\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9\u3011"},"content":{"rendered":"<p>\u6771\u5317\u5927\u5b66\u6771\u5317\u30e1\u30c7\u30a3\u30ab\u30eb\u30fb\u30e1\u30ac\u30d0\u30f3\u30af\u6a5f\u69cb\u30b2\u30ce\u30e0\u89e3\u6790\u90e8\u9580\u306e\u9577\ufa11\u6b63\u6717\u6559\u6388\u3001\u6cb3\u5408\u6d0b\u4ecb\u8b1b\u5e2b\u3089\u306f\u3001\u65e5\u672c\u4eba\u96c6\u56e3\u306e\u3082\u3064SNP\u3092\u5168\u30b2\u30ce\u30e0\u9818\u57df\u3092\u7db2\u7f85\u3057\u9ad8\u7cbe\u5ea6\u3067\u53d6\u5f97\u3067\u304d\u308b\u3001\u65e5\u672c\u4eba\u306b\u6700\u9069\u5316\u3055\u308c\u305fSNP\u30a2\u30ec\u30a4\u300c\u30b8\u30e3\u30dd\u30cb\u30ab\u30a2\u30ec\u30a4<sup>\u00ae<\/sup>\u300d\u306e\u8a2d\u8a08\u306b\u4e16\u754c\u3067\u521d\u3081\u3066\u6210\u529f\u3057\u307e\u3057\u305f\u3002<br \/>\n\u30b8\u30e3\u30dd\u30cb\u30ab\u30a2\u30ec\u30a4<sup>\u00ae<\/sup>\u306e\u8a2d\u8a08\u306f\u3001\u6771\u5317\u30e1\u30c7\u30a3\u30ab\u30eb\u30fb\u30e1\u30ac\u30d0\u30f3\u30af\u8a08\u753b\u306e\u30b3\u30db\u30fc\u30c8\u8abf\u67fb\u306b\u5354\u529b\u3057\u305f1,070\u4eba\u5206\u306e\u5168\u30b2\u30ce\u30e0\u60c5\u5831\u3092\u6d3b\u7528\u3057\u3001\u72ec\u81ea\u306eSNP\u9078\u629e\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u3092\u958b\u767a\u30fb\u5b9f\u88c5\u3057\u3066\u30b9\u30fc\u30d1\u30fc\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u4e0a\u3067\u89e3\u6790\u3059\u308b\u3053\u3068\u3067\u5b9f\u73fe\u3055\u308c\u307e\u3057\u305f\u3002<br \/>\n\u907a\u4f1d\u5b50\u578b\u30a4\u30f3\u30d4\u30e5\u30c6\u30fc\u30b7\u30e7\u30f3\uff08\u4ee5\u4e0b\u3001\u30a4\u30f3\u30d4\u30e5\u30c6\u30fc\u30b7\u30e7\u30f3\uff09\u6280\u8853\u3092\u7528\u3044\u308b\u3053\u3068\u3067\u7d0466\u4e07\u500b\u306eSNP\u3092\u642d\u8f09\u3057\u305f\u30b8\u30e3\u30dd\u30cb\u30ab\u30a2\u30ec\u30a4<sup>\u00ae<\/sup>\u304b\u3089\u6700\u59272,000\u4e07SNP\u3092\u53d6\u5f97\u53ef\u80fd\u3067\u3059\u3002<br \/>\n\u30b8\u30e3\u30dd\u30cb\u30ab\u30a2\u30ec\u30a4<sup>\u00ae<\/sup>\u306f\u65e2\u5b58\u306e\u540c\u7b49\u6570\u306eSNP\u304c\u642d\u8f09\u3055\u308c\u3066\u3044\u308b\u30a2\u30ec\u30a4\u3068\u6bd4\u3079\u3066\u30a4\u30f3\u30d4\u30e5\u30c6\u30fc\u30b7\u30e7\u30f3\u306e\u7cbe\u5ea6\u304c10%\u4ee5\u4e0a\u5411\u4e0a\u3057\u3001\u307e\u305f\u30013\u500d\u4ee5\u4e0a\u306e\u6570\u306eSNP\u304c\u642d\u8f09\u3055\u308c\u3066\u3044\u308b\u65e2\u5b58\u306eSNP\u30a2\u30ec\u30a4\u3068\u307b\u307c\u540c\u7b49\u307e\u305f\u306f\u305d\u308c\u4ee5\u4e0a\u306e\u6027\u80fd\u3092\u767a\u63ee\u3057\u307e\u3059\u3002<br \/>\n\u3053\u306e\u7814\u7a76\u306f\u3001\u65e5\u672c\u4eba\u306b\u56fa\u6709\u306a\u4f53\u8cea\u30fb\u75be\u60a3\u306e\u95a2\u9023\u907a\u4f1d\u5b50\u3092\u5927\u898f\u6a21\u306b\u63a2\u7d22\u7814\u7a76\u3059\u308b\u70ba\u306e\u57fa\u76e4\u89e3\u6790\u30c4\u30fc\u30eb\u3067\u3042\u308a\u3001\u65e5\u672c\u4eba\u306e\u500b\u5225\u5316\u4e88\u9632\u30fb\u533b\u7642\u7814\u7a76\u3092\u52a0\u901f\u3059\u308b\u91cd\u8981\u306a\u6210\u679c\u3067\u3059\u3002\u672c\u7814\u7a76\u6210\u679c\u306e\u8a73\u7d30\u306f\u30012015\u5e746\u670825\u65e5\uff08\u82f1\u56fd\u6642\u9593\uff09<i>Journal of Human Genetics<\/i>\u8a8c\u306e<a href=\"http:\/\/www.nature.com\/jhg\/journal\/vaop\/ncurrent\/full\/jhg201568a.html\">\u30aa\u30f3\u30e9\u30a4\u30f3\u7248<\/a>\u3067\u516c\u958b\u3055\u308c\u307e\u3057\u305f\u3002<br \/>\n<img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-3014\" src=\"http:\/\/nagasakilab.csml.org\/ja\/wp-content\/uploads\/2015\/06\/japonica_fix_20150716_web_400.jpg\" alt=\"japonica_fix_20150716_web_400\" width=\"400\" height=\"172\" srcset=\"https:\/\/nagasakilab.csml.org\/ja\/wp-content\/uploads\/2015\/06\/japonica_fix_20150716_web_400.jpg 400w, https:\/\/nagasakilab.csml.org\/ja\/wp-content\/uploads\/2015\/06\/japonica_fix_20150716_web_400-300x129.jpg 300w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>\u3010\u8ad6\u6587\u540d\u3011<br \/>\nYosuke Kawai, Takahiro Mimori, Kaname Kojima, Naoki Nariai, Inaho Danjoh, Rumiko Saito, Jun Yasuda, Masayuki Yamamoto, Masao Nagasaki<br \/>\n<a href=\"http:\/\/www.nature.com\/jhg\/journal\/vaop\/ncurrent\/full\/jhg201568a.html\">Japonica Array: Improved genotype imputation by designing a population-specific SNP array with 1,070 Japanese individuals<\/a><br \/>\n\u300c\u30b8\u30e3\u30dd\u30cb\u30ab\u30a2\u30ec\u30a4<sup>\u00ae<\/sup>\uff1a1,070\u4eba\u306e\u65e5\u672c\u4eba\u306e\u60c5\u5831\u306b\u57fa\u3065\u304f\u65e5\u672c\u4eba\u96c6\u56e3\u306b\u9069\u3057\u305fSNP\u30a2\u30ec\u30a4\u306e\u8a2d\u8a08\u306b\u3088\u308b\u30a4\u30f3\u30d4\u30e5\u30c6\u30fc\u30b7\u30e7\u30f3\u306e\u6539\u826f\u300d<br \/>\n\u63b2\u8f09\u4e88\u5b9a\u8a8c\uff1a<i>Journal of Human Genetics<\/i><\/p>\n<p>\u307e\u305f\u3001\u4eca\u56de\u306e\u767a\u8868\u306b\u3042\u308f\u305b\u3066\u3001\u7814\u7a76\u8005\u306e\u8208\u5473\u306e\u3042\u308bSNP\u304c\u642d\u8f09\u3055\u308c\u3066\u3044\u308b\u304b\u3092\u8a55\u4fa1\u3067\u304d\u308b\u3088\u3046\u306b\u30b8\u30e3\u30dd\u30cb\u30ab\u30a2\u30ec\u30a4<sup>\u00ae<\/sup>\u306b\u642d\u8f09\u3055\u308c\u3066\u3044\u308bSNP\u306e\u30ea\u30b9\u30c8\u306b\u3064\u3044\u3066<a href=\"http:\/\/nagasakilab.csml.org\/en\/japonica\">\u4e00\u822c\u516c\u958b<\/a>\u3092\u958b\u59cb\u3057\u307e\u3057\u305f\u3002<br \/>\n\u3055\u3089\u306b\u3001\u30b8\u30e3\u30dd\u30cb\u30ab\u30a2\u30ec\u30a4<sup>\u00ae<\/sup>\u3092\u7528\u3044\u3066\u672a\u642d\u8f09\u306eSNP\u304c\u3069\u306e\u7a0b\u5ea6\u306e\u7cbe\u5ea6\u3067\u30a4\u30f3\u30d4\u30e5\u30c6\u30fc\u30b7\u30e7\u30f3\u53ef\u80fd\u304b\u306b\u3064\u3044\u3066\u554f\u5408\u308f\u305b\u3092\u884c\u3046\u3053\u3068\u304c\u3067\u304d\u308b<a href=\"http:\/\/nagasakilab.csml.org\/en\/japonica\">\u30dd\u30fc\u30bf\u30eb\u30b5\u30a4\u30c8<\/a>\u3092\u516c\u958b\u3057\u307e\u3057\u305f\u3002<br \/>\n\u30b8\u30e3\u30dd\u30cb\u30ab\u30a2\u30ec\u30a4<sup>\u00ae<\/sup>\u306f\u3001\u682a\u5f0f\u4f1a\u793e \u6771\u829d\u3078\u306e\u30e9\u30a4\u30bb\u30f3\u30b9\u306e\u3082\u3068\u3001\u4e00\u822c\u306b\u30b8\u30a7\u30ce\u30bf\u30a4\u30d4\u30f3\u30b0\u30b5\u30fc\u30d3\u30b9\u306e\u63d0\u4f9b\u304c\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><a href=\"http:\/\/www.megabank.tohoku.ac.jp\/wp\/wp-content\/uploads\/2015\/06\/web_tohokuuniv-press150625_01.pdf\">\u00a0\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9\u672c\u6587pdf<\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6771\u5317\u5927\u5b66\u6771\u5317\u30e1\u30c7\u30a3\u30ab\u30eb\u30fb\u30e1\u30ac\u30d0\u30f3\u30af\u6a5f\u69cb\u30b2\u30ce\u30e0\u89e3\u6790\u90e8\u9580\u306e\u9577\ufa11\u6b63\u6717\u6559\u6388\u3001\u6cb3\u5408\u6d0b\u4ecb\u8b1b\u5e2b &hellip; <a href=\"https:\/\/nagasakilab.csml.org\/ja\/archives\/2947\">\u7d9a\u304d\u3092\u8aad\u3080 <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[],"class_list":["post-2947","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/posts\/2947","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/comments?post=2947"}],"version-history":[{"count":7,"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/posts\/2947\/revisions"}],"predecessor-version":[{"id":3017,"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/posts\/2947\/revisions\/3017"}],"wp:attachment":[{"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/media?parent=2947"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/categories?post=2947"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/tags?post=2947"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}