{"id":748,"date":"2013-03-08T16:30:22","date_gmt":"2013-03-08T07:30:22","guid":{"rendered":"http:\/\/nagasakilab.csml.org\/ja\/?p=748"},"modified":"2023-12-08T09:48:58","modified_gmt":"2023-12-08T00:48:58","slug":"%e7%ac%ac25%e5%9b%9e%e3%82%a4%e3%83%b3%e3%82%b7%e3%83%aa%e3%82%b3%e3%83%bb%e3%83%a1%e3%82%ac%e3%83%90%e3%83%b3%e3%82%af%e7%a0%94%e7%a9%b6%e4%bc%9a%e9%96%8b%e5%82%ac%e3%81%ae%e3%81%8a%e7%9f%a5%e3%82%89","status":"publish","type":"post","link":"https:\/\/nagasakilab.csml.org\/ja\/archives\/748","title":{"rendered":"\u7b2c25\u56de\u30a4\u30f3\u30b7\u30ea\u30b3\u30fb\u30e1\u30ac\u30d0\u30f3\u30af\u7814\u7a76\u4f1a\u958b\u50ac\u306e\u304a\u77e5\u3089\u305b\uff083\u67081 5\u65e5\uff09"},"content":{"rendered":"<p>\u7b2c25\u56de\u30a4\u30f3\u30b7\u30ea\u30b3\u30fb\u30e1\u30ac\u30d0\u30f3\u30af\u7814\u7a76\u4f1a\u3092\u4e0b\u8a18\u306e\u3068\u304a\u308a\u884c\u3044\u307e\u3059\u306e\u3067\u3054\u6848\u5185\u3044\u305f\u3057\u307e\u3059\u3002\u4eca\u56de\u306f\u30df\u30e5\u30f3\u30b9\u30bf\u30fc\u5927\u5b66\u306e\u30de\u30ab\u30ed\u30a6\u30b9\u30ad\u30fc\u5148\u751f\u3092\u8b1b\u5e2b\u3068\u3057\u3066\u304a\u8fce\u3048\u3057\u3001\u300c\u810a\u690e\u52d5\u7269\u306e\u30b0\u30ed\u30d3\u30f3\u306e\u9032\u5316\u300d\u306b\u3064\u3044\u3066\u8b1b\u6f14\u3057\u3066\u3044\u305f\u3060\u304d\u307e\u3059\u3002<\/p>\n<p>\u30fb\u65e5\u6642\uff1a\u5e73\u621025\u5e743\u670815\u65e5(\u91d1)\u300017\uff1a00\u201018\uff1a30<br \/>\n\u30fb\u5834\u6240\uff1a\u6771\u5317\u30e1\u30c7\u30a3\u30ab\u30eb\u30fb\u30e1\u30ac\u30d0\u30f3\u30af\u6a5f\u69cb2\u968e\u4f1a\u8b70\u5ba41  http:\/\/www.megabank.tohoku.ac.jp\/info\/access01.html<br \/>\n\u30fb\u6f14\u984c\uff1aNatural history of vertebrate globins<br \/>\n\u30fb\u8b1b\u5e2b\uff1a Prof. Wojciech Makalowski ( Institute of Bioinformatics, University of Muenster)<\/p>\n<p>\u30fb\u6982\u8981\uff1a\u3000Globins are small heme proteins that bind various external ligands, such<br \/>\nas oxygen or nitric oxide, and they are found in all kingdoms of life.<br \/>\nVertebrate genomes harbor seven different globin types, including prominent<br \/>\nhemoglobin (Hb) and myoglobin (Mb). Tetrameric Hb is present in<br \/>\nerythrocytes and transports oxygen via blood to the inner tissues. The<br \/>\nmonomeric, muscle-specific myoglobin, on the other hand, stores oxygen,<br \/>\nenhances the oxygen diffusion to the muscle cells and detoxifies nitric<br \/>\noxide. Five recent additions to vertebrate globin repertoire are cytoglobin<br \/>\n(Cygb), neuroglobin (Ngb), globin X (GbX), globin E (GbE) and globin Y<br \/>\n(GbY). It has been suggested that the GbE and Mb genes, as well as the GbY<br \/>\nand proto-Hb genes, are the paralogous products of tandem gene duplications<br \/>\nthat occurred early in the evolution of vertebrates. In contrast, Ngb and<br \/>\nGbX derive from independent duplication events that occurred before the<br \/>\nsplit of Deuterostomia and Protostomia. To date little is known regarding<br \/>\nthe functions of the novel globin proteins. I will focus on our recent<br \/>\nevolutionary studies of Ngb and GbX in which we demonstrated ancestry of<br \/>\nthese two globins reaching dating back to origins of metazoans.<\/p>\n<p>\u30fb\u4e16\u8a71\u4eba\uff1a\u5c71\u53e3\u7531\u7f8e\u3001\u9577\ufa11\u6b63\u6717   <\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7b2c25\u56de\u30a4\u30f3\u30b7\u30ea\u30b3\u30fb\u30e1\u30ac\u30d0\u30f3\u30af\u7814\u7a76\u4f1a\u3092\u4e0b\u8a18\u306e\u3068\u304a\u308a\u884c\u3044\u307e\u3059\u306e\u3067\u3054\u6848\u5185\u3044\u305f\u3057\u307e\u3059\u3002 &hellip; <a href=\"https:\/\/nagasakilab.csml.org\/ja\/archives\/748\">\u7d9a\u304d\u3092\u8aad\u3080 <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6,10],"tags":[],"class_list":["post-748","post","type-post","status-publish","format-standard","hentry","category-event","category-news"],"_links":{"self":[{"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/posts\/748","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/comments?post=748"}],"version-history":[{"count":3,"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/posts\/748\/revisions"}],"predecessor-version":[{"id":751,"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/posts\/748\/revisions\/751"}],"wp:attachment":[{"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/media?parent=748"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/categories?post=748"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nagasakilab.csml.org\/ja\/wp-json\/wp\/v2\/tags?post=748"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}