The 71st In Silico Megabank Research Seminar will be held on Friday, January 22, 2016. This Time, we will be welcoming Dr. Masahiro Kasahara, Graduate School of Frontier Sciences, The University of Tokyo as our lecturer, and he will be speaking on “Information Processing Technology for Genomic Sequencing”.
・Date/Time: January 22 (Friday) 5:00 pm‐6:30 pm
・Venue: Small Conference Room 2(3rd Floor), Tohoku Medical Megabank Building
・Title: Information Processing Technology for Genomic Sequencing
・Lecturer: Masahiro Kasahara（Graduate School of Frontier Sciences, The University of Tokyo）
＊This lecture is transferable as a class in the medical research-related lecture course.
・Abstract: Whole Genome Shotgun Method using PacBio RS, which is the world’s fist real-time single-molecule DNA sequencer for commercial use, is on the verge of becoming the de facto standard as the method to determine genomic sequencing in highly efficient and highly accurate manner. However, in comparison to the previous DNA sequencers, the read length is larger by one digit and the read error rate for base is higher by one digit or more. Thus, it has been difficult to perform genome assembly for large genomes by fully utilizing output information. In this lecture, the advancement of information processing technology to perform genome assembly, especially the error-correction techniques for base and the invention of data structure to correspond to large genomes will be introduced. In addition, the movement of germinating genomic sequencing technology using new observation technologies other than PacBio is to be introduced.
・Organizer: Tomoko Shibata, Masao Nagasaki