The 55th In Silico Megabank Research Seminar will be held on Friday, February 6.  This Time, we will be welcoming Dr. Yukinori Okada, Tokyo Medical and Dental University as our lecturer, and he will be speaking on “Elucidation of Disease Pathology, New Drug design, and Challenges to Epidemiology with Genetic Statistical Analysis ”.

・Date/Time : February 6 (Friday) 17:00‐18:30
・Venue : Small Conference Room 2(3rd Floor), Tohoku Medical Megabank Building
・Title : Elucidation of Disease Pathology, New Drug design, and Challenges to Epidemiology with Genetic Statistical Analysis
・Lecturer : Yukinori Okada (Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University)

＊This lecture is transferable as a class in the medical research-related lecture course.

・Abstract: Genetic Statistics is a research area that reveals the connection between the genetic information and trait information in living organisms through statistical analysis. It has been more than 10 years since the human genome sequences was mapped, and now we are in the era when genomic information of several thousands and hundreds of thousands of samples is available. Through massive human genome analysis based on such a large quantities of genomic information, various genes associated with the onset of human diseases have been identified.  In addition, genomic statistical analysis which reconciles acquired disease-related genes with various biological and medical databases and drug target gene groups in a cross-sectional manner have slowly revealed its contribution to the additional elucidation of disease pathology and new drug design though drug repositioning. Various approaches from the aspect of genetic statistical analysis has been implemented in order to resolve issues pointed out by epidemiologic studies such as changes in disease complications based on the combination of certain diseases. In this seminar, the results of genetic statistical analysis which we have conducted targeting at various human diseases are introduced and future prospect of human genomic analysis is discussed.

・Organizer : Yumi Yamguchi, Masao Nagasaki