December 18 ,2020, “Digenic mutations in ALDH2 and ADH5 impair formaldehyde clearance and cause a multisystem disorder, AMeD syndrome” has been published in the Science Advances.
September 23, 2020, “A multi-ethnic meta-analysis identifies novel genes, including ACSL5, associated with amyotrophic lateral sclerosis “ has been published online in the journal Communications Biology.
The published article has been uploaded here.
Professor Nagasaki will give a presentation at TECHNOLOGY LECTURES AND SYMPOSIUM on October 31, 2019
・ Dates : October 31(Thu),2019
・ Venue :The Omni Hotel, 1050 Sherbrooke St. W, Montreal, QC H3A 2R6, adjacent to the Mcgill Main Campus
・ Session &Theme : Health Innovation through genomics
・ Title: Genome cohort projects in Japan and biomedical analyses towards discoveries of diseases causing variants
・ Language : English
Professor Nagasaki and Dr. Olivier will give a presentation at ASHG2019 ( American Society of Human Genetic 2019) on October 18 (Fri) , 2019.
Professor Nagasaki was invited symposium at the 3rd JCS Council Forum on Basic CardioVascular Research(BCVR 2019) on September 8, 2019
・ Dates : September 8(Sun),2019
・ Venue : Room : Tokyo Convention Hall, Tokyo, Japan
・ Session &Theme : Genomics in Cardiology
・ Title: Development and application of biomedical methods to facilitate the detection of disease-causing variants based on whole genome data from Japanese
・ Language : English
Professor Nagasaki was invited lecture at the Genome Expo 2019 on August 28, 2019
・ Dates : August 28(Wed),2019
・ Venue : Room : U110, Engineering Bldg. 4, UNIST, Ulsan, Korea
・ Session & Theme : International Symposium on Human Genomics
・ Title: Genome cohort projects in Japan and biomedical analyses toward the discoveries of disease-causing variants
・ Language : English
Professor Nagasaki and Dr. Olivier gave a presentation at ESHG 2019(European Human Genetics Conference) on June 15-17, 2019
・ Dates : June 15(Sat)-17(Mon),2019
・ Venue :Gothenburg, Sweden
・ Poster title: HLA-VBSeq v2: enhancements of HLA genotyping accuracy from WGS data with full-length Japanese HLA sequences
・ Language : English
Nagasaki laboratory was moved from Tohoku University to Kyoto University form Apr/1/2019.
The website of Biomedical Information Analysis will be updated later.
Human Biosciences Unit for the Top Global Course Center for the Promotion of Interdisciplinary Education and Research (CPIER)
The 84th In Silico Megabank Research Seminar , Seminar of Toshiba-Tohoku University Joint Research on Quantum Cryptography Communication, and Security Seminar will be held together as below.
・Date/Time: December 14(Thursday) 6:00‐7:30 pm
・Venue: Conference Room(3rd Floor), Tohoku Medical Megabank Building
1. Explanation on the progress of the joint research (Masao Nagasaki, Tohoku University)
2. ・Lecturer: Masahide Sasaki（National Institute of Information and Communications Technology）
・Title: Super long-term secure secret sharing storage system using quantum key distribution technology
・Abstract: Genome information and life-critical medical information of individuals are relevant to multiple families’ ancestry and lineage as well as multiple generations. If such information is leaked, it can cause irredeemable situations. Therefore, it is essential to guarantee super long-term confidentiality (information is not exposed to others) and integrity (data is not altered or falsified) of such information over a century. However, it is not impossible to secure super long-term confidentiality and integrity with the current coding alone since it cannot completely prevent future safety to be compromised. On the other hand, well-combined protocols of quantum key distribution technology and secret sharing can actualize a secret sharing storage system that doesn’t allow any computer machines to decode and that can restore the original data correctly even if servers of some areas are damaged due to disasters or similar events. At National Institute of Information and Communications Technology (NICT), research and development of super long-term secure secret sharing storage system are currently carried out with cooperation of medical institutions. In this seminar, the mechanism of quantum key distribution technology is explained and the overview of secure secret sharing storage system, the progress status of the project, and future prospects are discussed.
3. ・Lecturer: Hideaki Sato（Toshiba Corporate Research & Development Center）
・Title: Quantum Cryptography Technology at Toshiba and Overview of the Joint Research with Tohoku University
・Abstract: Quantum cryptography communication is a cryptography communication system that actualizes the ultimate safety of data, and it enables realization of cryptography communication where data can never be decoded. Toshiba is currently taking initiatives to make a practical use of quantum cryptography technology developed by Cambridge Research Laboratory of Toshiba Research Europe Ltd. headquartered in England. Also, Toshiba has been conducting a joint research with Tohoku University on genomic data transmission since 2015. In this seminar, overview of progress of the joint research and current status of research and development of cutting-edge quantum cryptography communication device will be explained, and the future vision of systems utilizing quantum cryptography communication will be discussed.
4. Importance of security ( Takako Takai, Tohoku university)
5. Closing remarks (Fuji Nagami, Tohoku University)
＊This lecture is transferable as a class in the medical research-related lecture course.
・Organizer: Fuji Nagami, Takako Takai, Masao Nagasaki
We have released the new whole-genome reference panel with 3554 individuals of Japanese. The panel contains about qualified 37 million SNVs and about 13 million candidate SNVs. You can access the data from our integrative Japanese Genome Variation Database (iJGVD)
Tohoku University Tohoku Medical Megabank Organization
[NEWS] The locations and allele frequencies of SNVs of 3,554 Japanese individuals by whole genome sequences is available