The 17th In Silico Megabank Research Seminar will be held on Friday, November 16.

・Date/Time: November 16(Fri.) 17:00‐18:30
・Venue: Conference Room 1 (2F), Tohoku Medical Megabank Organization

・Title: Type 2 diabetic patients’ intestinal bacterial flora that is uncovered by the meta-genome-wide related analysis
・Lecturer: Shujiro Okuda (Ritsumeikan University)

・Abstract:
Type 2 diabetes is a kind of endocrine disease which has been rapidly increasing in the number of patients all over the world now.
In this study, I conducted a comparative study of the intestinal bacterial flora of the type 2 diabetic patients and that of the healthy persons using a new technique of meta-genome-wide related analysis. As a result, a number of markers related to type 2 diabetes were successfully identified. In addition, a possibility was suggested that type 2 diabetes could be diagnosed using these markers. From now on, a possibility of diagnosis and medical treatment with an application of the meta-genome-wide related markers to the other diseases is highly expected.
In general, meta-genome analysis generally requires high-speed sequence determination capability such as a next-generation sequencer, but it is still expensive and the process is also complicated.
I will also introduce a virtual meta-genome constructive method which does not need such a meta-genome sequence determination.